[CG] Laws of form

I'm quite confused on why people are interested in Laws of Form. What is LOF trying to do? Is it just rewriting logic or is there something more fundamental e.g. a universal algebraic system? What does GSB has to do with DNA, or DNA computing? What does Lou's work in topology has to do with GSB? What does GSB's theory has to do with knot theory? What does GSB's theory has to do with quaternions? How can GSB's theory be used for designing circuits? What's wrong with Frege?